Abnormal Fibrinogens
《英文msh詞典》Abnormal Fibrinogens
[同義詞] Abnormal Fibrinogens
[主題詞] Fibrinogens,Abnormal
[中文釋義] 異常纖維蛋白原類
[英文釋義] Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin,such as cleavage of the fibrinopeptides by thrombin,polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding,thrombosis or defective wound healing.
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